←　一覧へ戻る

---

Endotherial lipase (EL) transgenic rabbit

製作者

西島　和俊、範　江林

導入遺伝子

Endotherial lipase (EL) (Human)

キーワード

EL，脂質代謝，動脈硬化，肥満

特徴

ヒトELを発現している。

---

関連文献

• Wang, C., Nishijima, K., Kitajima, S., Niimi, M., Yan, H., Chen, Y., Ning, B., Matsuhisa, F., Liu, E., Zhang, J., Chen, Y. E., Fan. J.: Increased hepatic expression of endothelial lipase inhibits cholesterol diet-induced hypercholesterolemia and atherosclerosis in transgenic rabbits. Arterioscler. Thromb. Vasc. Biol. 37(7): 1282-1289, 2017.
• Wang, C., Niimi, M., Kitajima, S., Matsuhisa, F., Yan, H., Dong, S., Liang, J., Fan, J.: Sex hormones affect endothelial lipase-mediated lipid metabolism and atherosclerosis. Lipids in Health and Disease 18:226, 2019.（Open access）
• Yan, H., Niimi, M., Chuan Wang, C., Chen, Y., Zhou, H., Matsuhisa, F., Nishijima, K., Kitajima, S., Zhang, B., Yokomichi, H., Zhang, J., Chen, Y. E., Fan, J.: Endothelial lipase exerts its anti-atherogenic effect through increased catabolism of ?-VLDLs. J. Atheroscler. Thromb. 28: 157-168, 2021.

---

←　一覧へ戻る

---